Selected publications (2000 – present):

2023

Beliakov S.V., Blokhin V., Surkov S.A., Ugrumov M.V. LUHMES Cells: Phenotype Refinement and Development of an MPP+-Based Test System for Screening Antiparkinsonian Drugs. Int J Mol Sci. 2023 Jan 1;24(1):733. DOI: 10.3390/ijms24010733

Katunina E.A., Blokhin V., Nodel M.R., Pavlova E.N., Kalinkin AL., Kucheryanu VG., Alekperova L, Selikhova MV., Martynov M.Yu., Ugrumov M.V. Searching for biomarkers in the blood of patients at risk of developing Parkinson's disease at the prodromal stage // International Journal of Molecular Sciences. 2023, 24, 1842. https://doi.org/10.3390/ijms24031842

Kolacheva A., Pavlova E., Bannikova A., Bogdanov V., Troshev D., Ugrumov M. The Gene Expression of Proteins Involved in Intercellular Signaling and Neurodegeneration in the Substantia Nigra in a Mouse Subchronic Model of Parkinson’s Disease. // International Journal of Molecular Sciences. 2023. Vol. 24. Art. no 3027. DOI: 10.3390/ijms24033027

Troshev D, Bannikova A, Blokhin V, Pavlova E, Kolacheva A, Ugrumov M. Compensatory Processes in Striatal Neurons Expressing the Tyrosine Hydroxylase Gene in Transgenic Mice in a Model of Parkinson's Disease. Int J Mol Sci. 2023 Nov 13;24(22):16245. doi: 10.3390/ijms242216245.

Kolacheva A, Pavlova E, Bannikova A, Bogdanov V, Ugrumov M. Initial Molecular Mechanisms of the Pathogenesis of Parkinson's Disease in a Mouse Neurotoxic Model of the Earliest Preclinical Stage of This Disease. Int J Mol Sci. 2024 Jan 22;25(2):1354. doi: 10.3390/ijms25021354.

Blokhin V, Pavlova EN, Katunina EA, Nodel MR, Kataeva GV, Moskalets ER, Pronina TS, Ugrumov MV. Dopamine Synthesis in the Nigrostriatal Dopaminergic System in Patients at Risk of Developing Parkinson's Disease at the Prodromal Stage. J Clin Med. 2024 Feb 2;13(3):875. doi: 10.3390/jcm13030875.

2022

  1. Kolacheva A., Bannikova A., Pavlova E., Bogdanov V., Ugrumov M. Modeling of the Progressive Degradation of the Nigrostriatal Dopaminergic System in Mice to Study the Mechanisms of Neurodegeneration and Neuroplasticity in Parkinson's Disease. Int J Mol Sci. 2022 Dec 30;24(1):683. DOI: 10.3390/ijms24010683

  2. Troshev D., Blokhin V., Ukrainskaya V., Kolacheva A., Ugrumov M. Isolation of living dopaminergic neurons labeled with a fluorescent ligand of the dopamine transporter from mouse substantia nigra as a new tool for basic and applied research. Front Mol Neurosci. 2022;15:1020070. DOI:10.3389/fnmol.2022.1020070

  3. Pronina T., Pavlova E., Dil'mukhametova L., Ugrumov M. Development of the Periventricular Nucleus as a Brain Center, Containing Dopaminergic Neurons and Neurons Expressing Individual Enzymes of Dopamine Synthesis. Int J Mol Sci. 2022 Nov 24;23(23):14682. DOI: 10.3390/ijms232314682

  4. Troshev D., Bannikova A., Blokhin V., Kolacheva A., Pronina T., Ugrumov M.. Striatal Neurons Partially Expressing a Dopaminergic Phenotype: Functional Significance and Regulation. Int J Mol Sci. 2022;23(19):11054. DOI:10.3390/ijms231911054

  5. Blokhin V., Shupik M., Gutner U., Pavlova E., Lebedev A.T., Maloshitskaya O., Bogdanov V., Sokolov S., Alessenko A., Ugrumov M. The Sphingolipid Asset Is Altered in the Nigrostriatal System of Mice Models of Parkinson’s Disease. Biomolecules. 2022; 12(1):93. DOI: 10.3390/biom12010093

  6. Blokhin V.E., Lavrova A.V., Surkov S.A., Mingazov E.R., Gretskaya N.M., Bezuglov V.V., Ugrumov M.V. A New Method for the Visualization of Living Dopaminergic Neurons and Prospects for Using It to Develop Targeted Drug Delivery to These Cells. International Journal of Molecular Sciences. 2022; 23(7):3678. DOI: 10.3390/ijms23073678

  7. Kim A., Pavlova E., Kolacheva A., Bogdanov V., Dilmukhametova L., Blokhin V., Valuev L., Valuev I., Gorshkova M., Ugrumov M. Development of early diagnosis of Parkinson's disease on animal models based on the intranasal administration of α-methyl-p-tyrosine methyl ester in a gel system. Biomed Pharmacother. 2022 Jun;150:112944. DOI: 10.1016/j.biopha.2022.112944

  8. Kolacheva A., Alekperova L., Pavlova E., Bannikova A., Ugrumov M.V. Changes in Tyrosine Hydroxylase Activity and Dopamine Synthesis in the Nigrostriatal System of Mice in an Acute Model of Parkinson’s Disease as a Manifestation of Neurodegeneration and Neuroplasticity. Brain Sciences. 2022; 12(6):779. DOI: 10.3390/brainsci12060779

  9. Ugrumov M.V., Pavlova E.N., Kolacheva A.A., Dil’mukhametova L.K., Bogdanov V.V., Blokhin V.E., Pronina T.S. The Periventricular Nucleus as a Brain Center Containing Dopaminergic Neurons and Neurons Expressing Individual Enzymes of Dopamine Synthesis. International Journal of Molecular Sciences. 2022; 23(12):6739. DOI: 10.3390/ijms23126739

  10. Blokhin V.E., Pronina T.S., Surkov S.A., Murtazina A.R., Ugrumov M.V. Staining of Living Monoaminergic Neurons with 4-[4-(Dimethylamino) Styryl]-N-Methylpyridinium Iodide as a Tool for Studying Their Topography and Functions. Neurochem. J. 2022, 16, 155–160. DOI: 10.1134/S1819712422020040

  11. Rudenok M.M., Shadrina M.I., Filatova E.V., Rybolovlev I.N., Nesterov M.S., Abaimov D.A., Ageldinov R.A., Kolacheva A.A., Ugrumov M.V., Slominsky P.A., Alieva A.K.. Expression Analysis of Genes Involved in Transport Processes in Mice with MPTP-Induced Model of Parkinson's Disease//Life (Basel). 2022. Vol. 12. Is. 5. P. 751. DOI: 10.3390/life12050751

2021

  1. Gusev E.I., Katunina E.A., Martinov M.Y., Blokhin V.E., Kalinkin A.L., Alesenko A.V., Nodel M.R., Malykhina E.A., Titova N.V., Katunin D.A., Shupik M.A., Gutner U.A., Maloshitskaya O.A., Sokolov S.A., Kucheryanu V.G., Pavlova E.N., Ugrumov M.V. Development of Early Diagnosis of Parkinson’s Disease Using Premotor Symptoms and Blood Changes as Biomarkers//Neuroscience and Behavioral Physiology. 2021. Vol. 51. P. 1050-1058. DOI: 10.1007/s11055-021-01164-5

  2. Alessenko A.V., Blokhin V.E., Shupik M.A., Gutner U.A., Lebedev A.T., Maloshitskaya O.A., Sokolov S.A., Ugrumov M.V. Changes in the Content of Sphingolipids in the Nigrostriatal Dopaminergic System in the Brain of Mice with a Neurotoxic Model of Parkinson's Disease//Neurochemical Journal. 2021. Vol. 15. Is. 2. P. 175-180. DOI 10.1134/S1819712421020021.

  3. Blokhin V.E., Ugryumov M.V. Alpha-Synuclein in the Blood of Mice in a Neurotoxic Model of Parkinson's Disease//Neurochemical Journal. 2021. Vol. 15. Is. 1. P. 18-23. DOI: 10.1134/S1819712421010025

  4. Gusev E.I., Blokhin V.E., Vartanov S.A., Martinov M.Y., Katunina E.A., Alesenko A.V., Denisova I.A., Pavlova E.N., Polterovich, V.M., Kucheryanu, V.G., Shupik M.A., Nodel M.R., h, Kalinkin A.L., Sokolov S.A., Chubarova T.V. Shakleina M.V., Pronina T.S., Ugrumov M.V. Development of early diagnosis of Parkinson’s disease and comprehensive economic analysis of the effect of its implementation//Zhurnal Nevrologii i Psihiatrii imeni S.S. Korsakova. 2021. Vol. 121. Is. 1. P. 9-20. DOI: 10.17116/jnevro20211210119

  5. Kim A.R., Pavlova E.N., Blokhin V.E., Bogdanov V.V., Ugrumov M.V. A Monoiodotyrosine Challenge Test in a Parkinson's Disease Model//Acta Naturae. 2021. 1 Vol. 13. Is. 3. P. 106-109. DOI: 10.32607/actanaturae.11399

  6. Murtazina A.R., Bondarenko N.S., Pronina T.S., Chandran K.I., Bogdanov V.V., Dilmukhametova L.K., Ugrumov M.V. A Comparative Analysis of CSF and the Blood Levels of Monoamines As Neurohormones in Rats during Ontogenesis//Acta Naturae. 2021. Vol. 13. № 4 (51). Р. 89-97. DOI: 10.32607/actanaturae.11516

  7. Murtazina A.R., Pronina T.S., Chandran K.I., Dilmukhametova L.K., Bondarenko N.S., Bogdanov V.V., Blohin V.V., Ugrumov M.V. Hypothesis on the Endocrine System of the Brain: Evidence for the Regulated Delivery of Neurohormones from the Brain to the Cerebrospinal Fluid and Vice Versa in Neonatal and Prepubertal Periods of Ontogenesis//Russian Journal of Developmental Biology. 2021. Vol. 52 No. 6. P. 424-431. DOI: 10.1134/S1062360421060096

  8. Bogdanov V., Kim A., Nodel M., Pavlenko T., Pavlova E., Blokhin V., Chesnokova N., Ugrumov M. A Pilot Study of Changes in the Level of Catecholamines and the Activity of α-2-Macroglobulin in the Tear Fluid of Patients with Parkinson's Disease and Parkinsonian Mice//International Journal of Molecular Sciences. 2021. Vol. 22. Is. 9. Art. no. 4736. DOI: 10.3390/ijms22094736.

2020

  1. Ugrumov M. Development of early diagnosis of Parkinson's disease: Illusion or reality? [published online ahead of print, 2020 Jun 29]. CNS Neurosci Ther. 2020;10.1111/cns.13429. doi:10.1111/cns.13429

  2. Pronina TS, Kolacheva AA, Dil'muhametova LK, Nikishina YO, Suhinich KK, Ugrumov MV. Characteristic of Dopamine-Producing System and Dopamine Receptors in the Suprachiasmatic Nucleus in Rats in Ontogenesis. Dokl Biochem Biophys. 2020;490(1):34-37. doi:10.1134/S1607672920010123

  3. Pavlenko TA, Chesnokova NB, Nodel MR, Kim AR, Ugrumov MV. Molecular Mechanisms and Clinical Manifestations of Catecholamine Dysfunction in the Eye in Parkinson's Disease As a Basis for Developing Early Diagnosis. Acta Naturae. 2020;12(2):52-62. doi:10.32607/actanaturae.10906

  4. Alieva A, Rudenok M, Filatova E, Karabanov A, Doronina O, Doronina K, Kolacheva A, Ugrumov M, Illarioshkin S, Slominsky P, Shadrina M. VCP expression decrease as a biomarker of preclinical and early clinical stages of Parkinson's disease. Sci Rep. 2020;10(1):827. Published 2020 Jan 21. doi:10.1038/s41598-020-57938-3

  5. Pronina T.S, Dil'mukhametova L.K., Nikishina Yu.O., Murtazina A.R., Ugryumov M.V. Synthesis of Dopamine by Non-Dopaminergic Neurons Containing Aromatic Amino Acid Decarboxylase in the Suprachiasmatic Nucleus of Rats in Ontogeny//Neurochemical Journal. – 2020. – Vol. 14. – Is. 2. – P. 173-179. DOI: 10.1134/S1819712420020099

  6. Pronina T.S., Kolacheva A.A., Dil'muhametova L.K., Nikishina Y.O., Suhinich K.K., Ugrumov M.V. Characteristic of Dopamine-Producing System and Dopamine Receptors in the Suprachiasmatic Nucleus in Rats in Ontogenesis//Dokl Biochem Biophys. – 2020. – Vol. 490. – Is. 1. – P. 34-37. DOI: 10.1134/S1607672920010123

  7. Pronina T.S., Nikishina Yu.O., Dil'mukhametova L.K., Murtazina A.R., Ugryumov M.V. Synthesis of L-Dihydroxyphenylalanine by Monoenzymatic Tyrosine Hydroxylase-Containing Nerve Fibers in the Suprachiasmatic Nucleus in Rats during Ontogeny//Neurochemical Journal. – 2020. – Vol. 14. – Is. 2. – P. 167-173. DOI: 10.1134/S1819712420020087

2019

  1. Safandeev VV, Kolacheva AA, Ugrumov MV. Estimation of Metabolism of Catecholamines in Peripheral Organs As an Indicator of Their Desympathization under the Influence of Neurotoxins. Dokl Biochem Biophys. 2019;486(1):171-174. doi:10.1134/S1607672919030037

  2. Murtazina AR, Nikishina YO, Bondarenko NS, Dil'mukhametova LK, Sapronova AY, Ugrumov MV. Developing brain as a source of circulating norepinephrine in rats during the critical period of morphogenesis. Brain Struct Funct. 2019;224(9):3059-3073. doi:10.1007/s00429-019-01950-5

  3. Murtazina AR, Nikishina YO, Dil'mukhametova LK, Sapronova AY, Ugrumov MV. The Role of the Brain in the Regulation of Peripheral Noradrenaline-producing Organs in Rats During Morphogenesis. Dokl Biochem Biophys. 2019;486(1):243-246. doi:10.1134/S1607672919030207

  4. Mingazov ER, Pavlova EN, Surkov SA, Ugrumov MV. Proteins of the Vesicular Cycle as a Marker of Neuroplasticity of Dopaminergic Neurons in the Substantia Nigra of the Brain. Dokl Biochem Biophys. 2019;489(1):399-402. doi:10.1134/S1607672919060115

  5. Alexander Kim, Razina Nigmatullina, Zuleikha Zalyalova, Natalia Soshnikova, Alexey Krasnov, Nadezhda Vorobyeva, Sofia Georgieva, Vladimir Kudrin, Viktor Narkevich, Michael Ugrumov. Upgraded Methodology for the Development of Early Diagnosis of Parkinson's Disease Based on Searching Blood Markers in Patients and Experimental Models. Mol Neurobiol. 2019;56(5):3437-3450. doi:10.1007/s12035-018-1315-2

  6. Kim AR, Nodel MR, Pavlenko TA, Chesnokova NB, Yakhno NN, Ugrumov MV. Tear Fluid Catecholamines As Biomarkers of the Parkinson's Disease: A Clinical and Experimental Study. Acta Naturae. 2019;11(4):99-103. doi:10.32607/20758251-2019-11-4-99-103

  7. L A Katargina, N A Osipova, A Y Panova, A V Petrovskaya, Y O Nikishina, A R Murtazina, M V Ugrumov. The Role of Catecholamines in the Development of Pathological Retina Neovascularization in an Experimental Model of Retinopathy of Prematurity in Rats. Dokl Biochem Biophys. 2019;489(1):373-376. doi:10.1134/S160767291906005X

2018

1.       T A Pavlenko, A R Kim, A Yu Kurina, N G Davydova, E M Kolomojceva, N B Chesnokova, M V Ugrumov. Éndoteliny i dofamin v sleznoĭ zhidkosti v otsenke neĭrovaskuliarnykh narusheniĭ pri glaukome [Endothelins and dopamine levels in tears for assessment of neurovascular disorders in glaucoma]. Vestn Oftalmol. 2018;134(4):41-46. doi:10.17116/oftalma201813404141

2.       Eduard R Mingazov, Gulnara R Khakimova, Elena A Kozina, Alexei E Medvedev, Olga A Buneeva, Ara S Bazyan, Michael V Ugrumov. MPTP Mouse Model of Preclinical and Clinical Parkinson's Disease as an Instrument for Translational Medicine. Mol Neurobiol. 2018;55(4):2991-3006. doi:10.1007/s12035-017-0559-6

3.       Kurtova AI, Dil'mukhametova LK, Mingazov ER, Ugrumov MV. General Sources of Dopamine As a Potential Morphogenic Factor in the Developing Striatum of Rats. Dokl Biochem Biophys. 2018;479(1):123-126. doi:10.1134/S1607672918020199

4.       Kolacheva AA, Ugrumov MV. Dopamine Synthesis as a Mechanism of Brain Plasticity in Nigrostriatal System Pathology. Dokl Biochem Biophys. 2018;479(1):83-86. doi:10.1134/S1607672918020096

5.       Kim AR, Pavlenko TA, Katargina LA, Chesnokova NB, Ugrumov MV. Biochemical and Functional Changes in the Eye As a Manifestation of Systemic Degeneration of the Nervous System in Parkinsonism. Acta Naturae. 2018;10(3):62-67.

2017

1.       Murtazina AR, Nikishina YO, Bondarenko NS, Sapronova AY, Volina EV, Ugrumov MV. Gene expression and content of enzymes of noradrenaline synthesis in the rat organ of Zuckerkandl at the critical period of morphogenesis. Dokl Biochem Biophys. 2017;474(1):200-203. doi:10.1134/S1607672917030097

2.       Kurina AU, Pronina TS, Dilmukhametova LK, Maleev GV, Ugrumov MV. Cooperative Synthesis of Dopamine in Rat Mediobasal Hypothalamus as a Compensatory Mechanism in Hyperprolactinemia. Biochemistry (Mosc). 2017;82(3):366-372. doi:10.1134/S0006297917030154

3.       Kryukova EV, Shelukhina IV, Kolacheva AA, et al. Vozmozhnoe uchastie neĭronal'nykh nikotinovykh atsetilkholinovykh retseptorov v kompensatornykh mekhanizmakh mozga na rannikh stadiiakh bolezni Parkinsona [Possible involvement of neuronal nicotinic acetylcholine receptors in compensatory brain mechanisms at early stages of Parkinson's disease]. Biomed Khim. 2017;63(3):241-247. doi:10.18097/PBMC20176303241

4.       Kozina EA, Kim AR, Kurina AY, Ugrumov MV. Cooperative synthesis of dopamine by non-dopaminergic neurons as a compensatory mechanism in the striatum of mice with MPTP-induced Parkinsonism. Neurobiol Dis. 2017;98:108-121. doi:10.1016/j.nbd.2016.12.005

5.       Khakimova GR, Kozina EA, Kucheryanu VG, Ugrumov MV. Reversible Pharmacological Induction of Motor Symptoms in MPTP-Treated Mice at the Presymptomatic Stage of Parkinsonism: Potential Use for Early Diagnosis of Parkinson's Disease. Mol Neurobiol. 2017;54(5):3618-3632. doi:10.1007/s12035-016-9936-9

6.       Chesnokova NB, Pavlenko TA, Ugrumov MV. Patologiia organa zreniia kak odno iz proiavleniĭ bolezni Parkinsona [Ophthalmic disorders as a manifestation of Parkinson's disease]. Zh Nevrol Psikhiatr Im S S Korsakova. 2017;117(9):124-131. doi:10.17116/jnevro201711791124-131

7.       Bondarenko NS, Murtazina AR, Nikishina YO, Sapronova AY, Ugrumov MV. Molecular mechanisms of synthesis of noradrenaline as an inducer of development in the adrenal glands of rats in ontogenesis. Dokl Biochem Biophys. 2017;472(1):23-26. doi:10.1134/S1607672917010070

8.       N S Bondarenko, L K Dilmukhametova, A Yu Kurina, A R Murtazina, A Ya Sapronova, A P Sysoeva, M V Ugrumov. Plasticity of Central and Peripheral Sources of Noradrenaline in Rats during Ontogenesis. Biochemistry (Mosc). 2017;82(3):373-379. doi:10.1134/S0006297917030166

9.       Alieva AK, Filatova EV, Kolacheva AA, Rudenok MM, Slominsky PA, Ugrumov MV, Shadrina MI.. Transcriptome Profile Changes in Mice with MPTP-Induced Early Stages of Parkinson's Disease. Mol Neurobiol. 2017;54(9):6775-6784. doi:10.1007/s12035-016-0190-y

2016

1.       N V Soshnikova, N E Vorob'eva, A A Kolacheva, D Y Gurskiy, R R Nigmatullina, Z A Zalyalova, S G Georgieva, M V Ugrumov. [Ratio of transcription factor PHF10 splice variants in lymphocytes as a molecular marker of Parkinson's disease]. Mol Biol (Mosk). 2016;50(4):695-702. doi:10.7868/S0026898416040133

2.       Nikishina YO, Sapronova AY, Ugrumov MV. The Effect of Dopamine Secreted by the Brain into the Systemic Circulation on Prolactin Synthesis by the Pituitary gland in Ontogenesis. Acta Naturae. 2016;8(3):111-117.

3.       Murtazina AR, Nikishina YO, Bondarenko NS, Sapronova AJ, Ugrumov MV. Signal molecules during the organism development: Central and peripheral sources of noradrenaline in rat ontogenesis. Dokl Biochem Biophys. 2016;466:74-76. doi:10.1134/S160767291601018X

4.       Mingazov ER, Ugrumov MV. Gene expression of proteins of the vesicle cycle in the striatum and motor cortex under functional failure of nigrostriatal system. Dokl Biochem Biophys. 2016;470(1):313-315. doi:10.1134/S160767291605001X

5.       Mingazov ER, Ugrumov MV. Gene expression of proteins of the vesicle cycle in dopaminergic neurons in modeling of Parkinson's disease. Dokl Biochem Biophys. 2016;468(1):206-208. doi:10.1134/S1607672916030133

6.       Kurina AU, Pronina TS, Kudrin VS, Ugrumov MV. Missing proof of cooperative synthesis of dopamine by non-dopaminergic neurons. Dokl Biochem Biophys. 2016;468(1):197-199. doi:10.1134/S1607672916030108

7.       Bondarenko NS, Murtazina AR, Dil'mukhametova LK, Ikonopistseva MA, Volina EV, Ugrumov MV. Secretory activity of the brain and peripheral organs: Spontaneous and stimulated release of noradrenaline in the ontogenesis of rats. Dokl Biochem Biophys. 2016;467(1):153-156. doi:10.1134/S1607672916020204

2015

1.       Zubova YO, Bondarenko NS, Sapronova AJ, Ugrumov MV. Modeling of chronic selective inhibition of noradrenaline synthesis in the brain of neonatal rats. Dokl Biochem Biophys. 2015;461:123-126. doi:10.1134/S1607672915020155

2.       Ugrumov MV. [Development of preclinical diagnosis and preventive treatment of neurodegenerative diseases]. Zh Nevrol Psikhiatr Im S S Korsakova. 2015;115(11):4-14. doi:10.17116/jnevro20151151114-14

3.       V M Kovalzon, M V Ugrumov, T S Pronina, V B Dorokhov, A I Manolov, V V Dolgikh, Y V Ukraintseva, L S Moiseenko, M G Poluektov, A L Kalinkin. [Early Stages of Parkinson's Disease: Comparative Characteristics of Sleep-Wakefulness Cycle in Patients and Model Animals]. Fiziol Cheloveka. 2015;41(6):114-118.

4.       Khakimova GR, Degtyareva EA, Kozina EA, Kucheryanu VG, Ugrumov MV. "Provocation test" as a novel approach to early diagnosis of Parkinson's disease. Dokl Biol Sci. 2015;460:17-19. doi:10.1134/S0012496615010160

5.       Bondarenko NS, Zubova YO, Sapronova AY, Volina EV, Ugrumov MV. Role of Adenohypophysotropic Neurohormones in Endocrine Paraadenohypophysial Regulation of Peripheral Target Organs in Rat Ontogeny. Bull Exp Biol Med. 2015;159(3):293-296. doi:10.1007/s10517-015-2945-2

2014

1.       Yulia Z, Diana N, Anna S, Michael U. Brain as an endocrine source of circulating 5-hydroxytryptamine in ontogenesis in rats. Mol Cell Endocrinol. 2014;393(1-2):92-98. doi:10.1016/j.mce.2014.06.006

2.       M Ugrumov, J Taxi, T Pronina, A Kurina, A Sorokin, A Sapronova, A Calas. Neurons expressing individual enzymes of dopamine synthesis in the mediobasal hypothalamus of adult rats: functional significance and topographic interrelations. Neuroscience. 2014;277:45-54. doi:10.1016/j.neuroscience.2014.06.051

3.       Saifetyarova YY, Melnikova VI, Sapronova AY, Volina EV, Ugrumov MV. The developing brain as an endocrine source of norepinephrine in the blood. Dokl Biol Sci. 2014;454:5-8. doi:10.1134/S0012496614010116

4.       Elena A Kozina, Gulnara R Khakimova, Vitaly G Khaindrava, Valeriayn G Kucheryanu, Nadezhda E Vorobyeva, Alexey N Krasnov, Sophia G Georgieva, Lidiya Kerkerian-Le Goff, Michael V Ugrumov. Tyrosine hydroxylase expression and activity in nigrostriatal dopaminergic neurons of MPTP-treated mice at the presymptomatic and symptomatic stages of parkinsonism. J Neurol Sci. 2014;340(1-2):198-207. doi:10.1016/j.jns.2014.03.028

5.       Filatova EV, Shadrina MI, Alieva AKh, Kolacheva AA, Slominsky PA, Ugrumov MV. Expression analysis of genes of ubiquitin-proteasome protein degradation system in MPTP-induced mice models of early stages of Parkinson's disease. Dokl Biochem Biophys. 2014;456(1):116-118. doi:10.1134/S1607672914030107

2013

1.       Ugrumov MV. Brain neurons partly expressing dopaminergic phenotype: location, development, functional significance, and regulation. Adv Pharmacol. 2013;68:37-91. doi:10.1016/B978-0-12-411512-5.00004-X

2012

1.       Ugrumov MV, Saifetyarova JY, Lavrentieva AV, Sapronova AY. Developing brain as an endocrine organ: secretion of dopamine. Mol Cell Endocrinol. 2012;348(1):78-86. doi:10.1016/j.mce.2011.07.038

2.       Melnikova VI, Lyupina YV, Lavrentieva AV, Sapronova AY, Ugrumov MV. Synthesis of dopamine in non-dopaminergic neurons of the mediobasal hypothalamus of adult rats. Dokl Biol Sci. 2012;446:286-289. doi:10.1134/S0012496612050122

2011

1.       Ugrumov MV, Khaindrava VG, Kozina EA, Kucheryanu VG, Bocharov EV, Kryzhanovsky GN, Kudrin VS, Narkevich VB, Klodt PM, Rayevsky KS, Pronina TS. Modeling of presymptomatic and symptomatic stages of parkinsonism in mice. Neuroscience. 2011;181:175-188. doi:10.1016/j.neuroscience.2011.03.007

2.       Khakimova GR, Kozina EA, Sapronova AY, Ugrumov MV. Dopamine synthesis in the nigrostriatal system at the presymptomatic and early symptomatic stages in parkinsonian mice. Dokl Biol Sci. 2011;440:284-286. doi:10.1134/S0012496611050231

3.       Khaindrava V, Salin P, Melon C, Ugrumov M, Kerkerian-Le-Goff L, Daszuta A. High frequency stimulation of the subthalamic nucleus impacts adult neurogenesis in a rat model of Parkinson's disease. Neurobiol Dis. 2011;42(3):284-291. doi:10.1016/j.nbd.2011.01.018

4.       V G Khaindrava, E A Kozina, V S Kudrin, V G Kucheryanu, P D Klodt, V B Narkevich, E V Bocharov, A K Nanaev, G N Kryzhanovsky, K S Raevskii, M V Ugrumov. Experimental modeling of preclinical and clinical stages of Parkinson's disease. Bull Exp Biol Med. 2011;150(5):566-569. doi:10.1007/s10517-011-1191-5

5.       Abramova MA, Calas A, Ugrumov M. Vasopressinergic neurons of the supraoptic nucleus in perinatal rats: reaction to osmotic stimulation and its regulation. Brain Struct Funct. 2011;215(3-4):195-207. doi:10.1007/s00429-010-0290-9

2010

1.       Ugrumov MV. Developing brain as an endocrine organ: a paradoxical reality. Neurochem Res. 2010;35(6):837-850. doi:10.1007/s11064-010-0127-1

2009

1.       Ugrumov MV. Synthèse de monoamines par des neurones non-monoaminergiques. Illusion ou réalité ? [Synthesis of monoamines by non-monoaminergic neurons: illusion or reality?]. J Soc Biol. 2009;203(1):75-85. doi:10.1051/jbio:2009013

2.       Ugrumov MV. Non-dopaminergic neurons partly expressing dopaminergic phenotype: distribution in the brain, development and functional significance. J Chem Neuroanat. 2009;38(4):241-256. doi:10.1016/j.jchemneu.2009.08.004

3.       Izvolskaia M, Duittoz AH, Tillet Y, Ugrumov MV. The influence of catecholamine on the migration of gonadotropin-releasing hormone-producing neurons in the rat foetuses. Brain Struct Funct. 2009;213(3):289-300. doi:10.1007/s00429-008-0197-x

4.       Dygalo NN, Kalinina TS, Chernolovskaya EL, Zenkova MA, Shishkina GT, Ugrumov MV. Experimental approach to study of the gonadotropin-releasing hormone function by knockdown of its expression with RNA interference in ontogenesis. Dokl Biol Sci. 2009;426:213-215. doi:10.1134/s0012496609030065

2008

1.       Abramova MA, Ugryumov MV, Kalas A. Vasopressinergic neurons in rats in ontogenesis: responses to salt loading and their modulation by noradrenergic afferents. Neurosci Behav Physiol. 2008;38(6):605_611.

2007

1.       Lavrent'eva AV, Mel'nikova VI, Sapronova AY, Proshlyakova EV, Voronova SN, Ugryumov MV. The brain is one of the most important sources of dopamine in the systemic circulation in the perinatal period of ontogenesis in rats. Neurosci Behav Physiol. 2007;37(9):909_914.

 2006

1.       Melnikova VI, Raison D, Hardin-Pouzet H, Ugrumov MV, Calas A, Grange-Messent V. Noradrenergic regulation of galanin expression in the supraoptic nucleus in the rat hypothalamus. An ex vivo study. J Neurosci Res. 2006;83(5):857-863. doi:10.1002/jnr.20779

2.       Izvolskaia M, Duittoz AH, Ugrumov MV, Tillet Y. Tyrosine hydroxylase expression in the olfactory/respiratory epithelium in early sheep fetuses (Ovis aries). Brain Res. 2006;1083(1):29-38. doi:10.1016/j.brainres.2006.01.130

2005

1.       Michael V Ugrumov, Anna Ya Sapronova, Viktoria I Melnikova, Evgeniya V Proshlyakova, Elene I Adamskaya, Antonina V Lavrentieva, Diana I Nasirova, Vasilii N Babichev. Brain is an important source of GnRH in general circulation in the rat during prenatal and early postnatal ontogenesis. Comp Biochem Physiol A Mol Integr Physiol. 2005;141(3):271-279. doi:10.1016/j.cbpb.2005.04.009

2.       Eduardo J B Ramos, Irina V Romanova, Susumu Suzuki, Chung Chen, Michael V Ugrumov, Tomoi Sato, Carolina G Goncalves, Michael M Meguid. Effects of omega-3 fatty acids on orexigenic and anorexigenic modulators at the onset of anorexia. Brain Res. 2005;1046(1-2):157-164. doi:10.1016/j.brainres.2005.03.052

3.       Mirochnik V, Bosler O, Tillet Y, Calas A, Ugrumov M. Long-lasting effects of serotonin deficiency on differentiating peptidergic neurons in the rat suprachiasmatic nucleus. Int J Dev Neurosci. 2005;23(1):85-91. doi:10.1016/j.ijdevneu.2004.07.021

4.       Irina G Makarenko, Michael M Meguid, Louis Gatto, Chung Chen, Eduardo J B Ramos, Carolina G Goncalves, Michael V Ugrumov. Normalization of hypothalamic serotonin (5-HT 1B) receptor and NPY in cancer anorexia after tumor resection: an immunocytochemical study. Neurosci Lett. 2005;383(3):322-327. doi:10.1016/j.neulet.2005.04.031

5.       Makarenko IG, Ugrumov MV, Calas A. Axonal projections from the hypothalamus to the pituitary intermediate lobe in rats during ontogenesis: DiI tracing study. Brain Res Dev Brain Res. 2005;155(2):117-126. doi:10.1016/j.devbrainres.2004.12.007

6.       Irina G Makarenko, Michael M Meguid, Louis Gatto, Carolina G Goncalves, Eduardo J B Ramos, Chung Chen, Michael V Ugrumov. Hypothalamic 5-HT1B-receptor changes in anorectic tumor bearing rats. Neurosci Lett. 2005;376(2):71-75. doi:10.1016/j.neulet.2004.11.026

7.       Ershov PV, Ugrumov MV, Calas A, Krieger M, Thibault J. Degeneration of dopaminergic neurons triggers an expression of individual enzymes of dopamine synthesis in non-dopaminergic neurons of the arcuate nucleus in adult rats. J Chem Neuroanat. 2005;30(1):27-33. doi:10.1016/j.jchemneu.2005.04.001

2004

1.       Ugrumov MV, Melnikova VI, Lavrentyeva AV, Kudrin VS, Rayevsky KS. Dopamine synthesis by non-dopaminergic neurons expressing individual complementary enzymes of the dopamine synthetic pathway in the arcuate nucleus of fetal rats. Neuroscience. 2004;124(3):629-635. doi:10.1016/j.neuroscience.2004.01.002

2003

1.       Pronina T, Ugrumov M, Calas A, Seif I, Tramu G. Influence of monoamines on differentiating gonadotropin-releasing hormone neurones in foetal mice. J Neuroendocrinol. 2003;15(10):925-932. doi:10.1046/j.1365-2826.2003.01072.x

2.       T Pronina, M Ugrumov, E Adamskaya, T Kuznetsova, I Shishkina, V Babichev, A Calas, G Tramu, P Mailly, I Makarenko. Influence of serotonin on the development and migration of gonadotropin-releasing hormone neurones in rat foetuses. J Neuroendocrinol. 2003;15(6):549-558. doi:10.1046/j.1365-2826.2003.01029.x

3.       Makarenko IG, Meguid MM, Gatto L, Chen C, Ugrumov MV. Decreased NPY innervation of the hypothalamic nuclei in rats with cancer anorexia. Brain Res. 2003;961(1):100-108. doi:10.1016/s0006-8993(02)03850-7

4.       Bruneau G, Izvolskaia M, Ugrumov M, Tillet Y, Duittoz AH. Prolonged neurogenesis during early development of gonadotropin-releasing hormone neurones in sheep (Ovis Aries): in vivo and in vitro studies. Neuroendocrinology. 2003;77(3):177-186. doi:10.1159/000069505

2002

1.       M Ugrumov, T Pronina, P Ershov, W Wittkowski, C Gharib, J Gabrion, A Grigoriev. Influence of hypergravity on hypothalamic vasopressin and oxytocin neurons in rats. J Gravit Physiol. 2002;9(1):P45-P46.

2.       Ugrumov M, Melnikova V, Ershov P, Balan I, Calas A. Tyrosine hydroxylase- and/or aromatic L-amino acid decarboxylase-expressing neurons in the rat arcuate nucleus: ontogenesis and functional significance. Psychoneuroendocrinology. 2002;27(5):533-548. doi:10.1016/s0306-4530(01)00091-9

3.       Ugrumov MV. Magnocellular vasopressin system in ontogenesis: development and regulation. Microsc Res Tech. 2002;56(2):164-171. doi:10.1002/jemt.10021

4.       Christophe Masseguin 1, Lydia Siderenko, Tatiana Pronina, Petr Ershov, Anatoli Grigoriev, Mikhail Ugrumov, Jacqueline Gabrion. CSF-contacting epithelia in altered gravity: changes in apical structures and water channels expression. J Gravit Physiol. 2002;9(1):P301-P302.

5.       Makarenko IG, Meguid MM, Ugrumov MV. Distribution of serotonin 5-hydroxytriptamine 1B (5-HT(1B)) receptors in the normal rat hypothalamus. Neurosci Lett. 2002;328(2):155-159. doi:10.1016/s0304-3940(02)00345-2

6.       Ershov PV, Ugrumov MV, Calas A, Makarenko IG, Krieger M, Thibault J. Neurons possessing enzymes of dopamine synthesis in the mediobasal hypothalamus of rats. Topographic relations and axonal projections to the median eminence in ontogenesis. J Chem Neuroanat. 2002;24(2):95-107. doi:10.1016/s0891-0618(02)00019-4

7.       Ershov PV, Ugrumov MV, Calas A, Krieger M, Thibault J. Differentiation of tyrosine hydroxylase-synthesizing and/or aromatic L-amino acid decarboxylase-synthesizing neurons in the rat mediobasal hypothalamus: quantitative double-immunofluorescence study. J Comp Neurol. 2002;446(2):114-122. doi:10.1002/cne.10173

8.       Abramova M, Marsais F, Calas A, Thibault J, Ugrumov M. Dynamical study of tyrosine hydroxylase expression and its correlation with vasopressin turnover in the magnocellular neurons of the supraoptico-posthypophysial system under long-term salt loading of adult rats. Brain Res. 2002;925(1):67-75. doi:10.1016/s0006-8993(01)03260-7

2001

1.       Melnikova VI, Ugrumov MV, Proshlyakova EV, Calas A, Thibault J. Tyrosine hydroxylase expression in differentiating neurons of the rat arcuate nucleus: stimulatory influence of serotonin afferents. Neural Plast. 2001;8(4):271-284. doi:10.1155/NP.2001.271

2.       Makarenko IG, Ugrumov MV, Calas A. Axonal projections from the hypothalamus to the median eminence in rats during ontogenesis: DiI tracing study. Anat Embryol (Berl). 2001;204(3):239-252. doi:10.1007/s004290100181

2000

1.       Zakharova, L. ., Malyukova, I. ., Proshlyakova, E. ., Potapova, A. ., Sapronova, A. ., Ershov, P. ., & Ugrumov, M. Hypothalamo-pituitary control of the cell-mediated immunity in rat embryos: role of LHRH in regulation of lymphocyte proliferation. J Reprod Immunol. 2000;47(1):17-32. doi:10.1016/s0165-0378(00)00057-7

2.       Makarenko IG, Ugrumov MV, Derer P, Calas A. Projections from the hypothalamus to the posterior lobe in rats during ontogenesis: 1,1'-dioctadecyl-3,3,3', 3'-tetramethylindocarbocyanine perchlorate tracing study. J Comp Neurol. 2000;422(3):327-337. doi:10.1002/1096-9861(20000703)422:3<327::aid-cne1>3.0.co;2-9

3.       Balan IS, Ugrumov MV, Calas A, Mailly P, Krieger M, Thibault J. Tyrosine hydroxylase-expressing and/or aromatic L-amino acid decarboxylase-expressing neurons in the mediobasal hypothalamus of perinatal rats: differentiation and sexual dimorphism. J Comp Neurol. 2000;425(2):167-176. doi:10.1002/1096-9861(20000918)425:2<167::aid-cne1>3.0.co;2-k

4.       Abramova M, Calas A, Thibault J, Ugrumov M. Tyrosine hydroxylase in vasopressinergic axons of the pituitary posterior lobe of rats under salt-loading as a manifestation of neurochemical plasticity. Neural Plast. 2000;7(3):179-191. doi:10.1155/NP.2000.179